Definition: Wolfram Syndrome is a rare genetic disorder which is also known as DIDMOAD syndrome after its 4 most common features (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness). Everyone with Wolfram Syndrome will have optic atrophy at some stage, which means that the optic nerve wastes away and causes colour blindness and gradual loss of vision. Wolfram Syndrome is very rare and affects around 1 in 770,000 of the total UK population.

Category: eye condition

Credit: UK Wolfram Syndrome support group

Source: https://wolframsyndrome.co.uk/what-is-ws/